Manx Utilities says motorists face six months of misery as it improves the capital's sewage system.
Work on a 23-week project on the Old Castletown Road will start on Thursday.
Kewaigue's pumping station will be replaced, and work will take place on the Old Castletown Road and Heron & Brearley brewery site.
There'll be a number of road closures and traffic restrictions between Thursday, April 3 and Wednesday, April 16.
Police hunt pub spitter - do you recognise him?
Do you know this man?
Collection for Myanmar earthquake victims this weekend
The One World Centre is asking people to dig deep this weekend as it collects money to help people in Myanmar.
Child sex images investigations to get AI help
Police will use AI in future to judge how bad child sex images are.
FOI request shows overcrowding at prison
The Department of Home Affairs says the prison has almost 15 per cent more inmates than it was designed for.
Hiring advisors will save health money, says minister
The Island's health minister says hiring two external consultants will help Manx Care meet its budgets in future.
Dozens of extra salt bins this year, says minister
Infrastructure Minister Michelle Haywood says the Island's had an extra 21 salt bins to deal with freezing weather over the winter.
No data on minimum wage earners, says minister
Treasury Minister Alex Allinson says he doesn't know how many people were paid minimum wage last year - or how much they contributed in tax and National Insurance.
Foodbank looking for volunteers
Could you help those who've been badly hit by the cost of living crisis?
